Medicamentos de referência, genérico e similar: avaliação da qualidade dos comprimidos de captopril e enalapril

Edson Ferreira Chaves Medeiros, Lucas Vargas da Mota, Haline Gerica de Oliveira Alvim

Resumo


Este trabalho objetivou analisar a qualidade dos comprimidos e a relação entre os medicamentos de referência, genéricos e similares. Para estudo e coleta de dados, foram realizados testes físicos e físico-químicos de acordo com a farmacopéia brasileira 5º edição 2010. Os produtos analisados apresentaram resultados satisfatórios quanto aos aspectos visuais, teste de vazamento, determinação de peso médio em formas farmacêuticas sólidas, determinação de resistência mecânica através dos testes de dureza e friabilidade e teste de desintegração, demonstraram qualidade conforme com devidas especificações, estando adequados para o consumo.



Palavras-chave


Controle de Qualidade; Captopril; Enalapril; Genéricos; Similares.

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ISSN (Online): 2179-0981 / ISSN (Impresso): 2316-848X

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